Shizune is a Jōnin-level Kunoichi of Konohagakure. She has served as Tsunade's personal assistant for years. Shizune was also Tsunade's apprentice, becoming a talented medic-nin. Shizune remains quite close to Tsunade, being one of the few people Tsunade would trust with absolute certainty, and a fairly talented and capable ninja in her own right.